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目的:探讨肝硬化脾功能亢进患者骨髓象特点。方法:对患者行骨髓穿刺获得骨髓涂片,然后行瑞氏染色,进行显微镜检查。结果:肝硬化脾功能亢进56例骨髓象特点:多呈增生象,但有少数骨髓增生低下,细胞成熟障碍表现。主要表现为粒细胞系统和巨核细胞系统成熟障碍。骨髓有5种不同类型:脾功能亢进骨髓象35例(62.5%),缺铁性贫血12例(19.8%),继发性贫血5例(8.9%),大致正常3例(5.4%),再生障碍性贫血1例(3.4%)。结论:肝硬化脾功能亢进患者血液学异常原因较多,将骨髓穿刺术作为常规检查之一,可以指导临床治疗。
Objective: To investigate the bone marrow characteristics of patients with liver cirrhosis and hypersplenism. METHODS: Bone marrow smears were obtained from patients undergoing bone marrow aspirate and then subjected to Wright staining for microscopic examination. Results: Liver cirrhosis and hypersplenism 56 cases of bone marrow features: mostly hyperplasia, but a small number of bone marrow hyperplasia, cell dysfunction performance. Mainly manifested as the maturation of the granulocyte and megakaryocyte systems. There are five different types of bone marrow: 35 cases (62.5%) with spleen hyperthyroidism, 12 cases (19.8%) with iron deficiency anemia, 5 cases (8.9%) with secondary anemia, and 3 cases (5.4% Aplastic anemia in 1 case (3.4%). Conclusion: Hematological abnormalities in patients with liver cirrhosis and hypersplenism have many causes. Bone marrow as one of the routine tests, can guide clinical treatment.