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原发性恶性黑色素瘤(简称恶黑)恶黑的大多数病例位于皮肤,少数位于皮肤以外的粘膜、眼球色素膜和软脑膜等处。粘膜恶黑的黑色素含量常不高,约50％病例属于无色素性黑色素瘤,以致临床误诊率比皮肤恶黑高得多,病理诊断也较困难。由于粘膜恶黑不易早期发现,诊断困难以及难以根治切除,因此粘膜恶黑的予后也较皮肤恶黑差得多。鉴于国内关于粘膜恶黑只有个案或数例零星报道,为数很少,本文收集到35例粘膜恶黑(结合膜除外),并对其临床和病理资料加以分析研究,以期提高对粘膜恶黑的认识,掌握它的特点,仅供同道们参考。
Most cases of primary malignant melanoma (abbreviated as ebony black) are located on the skin, and a few are located on the mucosa outside the skin, the pigmented membrane of the eye, and the pia mater. The melanin content of mucous membranes is often not high, about 50% of cases are non-pigmented melanoma, so that the rate of clinical misdiagnosis is much higher than black skin, and pathological diagnosis is also more difficult. Due to the difficulty of early detection of dystrophic mucous membranes, difficult diagnosis, and difficulty in radical resection, the mucous membranes are much worse than black skin. In view of the fact that there are only few cases of sporadic reports of mucosal nausea in the country and few reports, 35 cases of dysentery were collected in this study (except for conjugation membranes), and their clinical and pathological data were analyzed and studied in an attempt to increase the severity of mucosal nausea. Understanding and mastering its characteristics are only for reference by fellow practitioners.