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目的评价~(99m)Tc-MIBI心/肝比值(H/L)对肝硬化患者预后判断。方法用回顾性队列研究方法,对所有进行H/L测定的肝硬化患者对其不同的Child-Pugh分级的H/L进行生存率分析。结果所有患者随访0.1~63个月,Child-PughA、B、C组的H/L值分别为0.85±0.15,0.99±0.19,1.15±0.27(F=5.09P<0.01),H/L≤1.0组的6个月、1年、2年的生存率明显较H/L儿>1.0组高(分别为:85.9%,57.4%,57.4%和50.0%,39.4%,19.7%,P<0.01),在Child-PughC级的患者中H/L≤1.0组的6个月、1年、2年的生存率明显较H/L>1.0对组高(分别为71.4%,42.9%,42.9%和27.3%,18.2%,0)。结论H/L是评价肝硬化患者预后的较为有效的指标,可以和Child-Pugh分级相互补充。
Objective To evaluate the prognostic value of ~ (99m) Tc-MIBI cardiac / hepatic ratio (H / L) in patients with liver cirrhosis. Methods A retrospective cohort study was performed to evaluate the survival of all H-L-treated patients with cirrhosis who had different Child-Pugh grades of H / L. Results All patients were followed up for 0.1 to 63 months. The values of H / L in Child-PughA, B and C groups were 0.85 ± 0.15, 0.99 ± 0.19 and 1.15 ± 0.27, respectively (F = 5.09P <0.01) The 6-month, 1-year and 2-year survival rates in the group were significantly higher than those in the H / L group> 1.0 (85.9%, 57.4%, 57.4% and 50.0%, 39.4% and 19.7, respectively %, P <0.01). The 6-month, 1-year and 2-year survival rates in H / L≤1.0 group were significantly higher than those in H / L> 1.0 group in Child-PughC class (71.4%, 42.9%, 42.9% and 27.3%, 18.2%, 0 respectively). Conclusion H / L is a more effective indicator to evaluate the prognosis of patients with liver cirrhosis, which can be complemented with Child-Pugh classification.