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目的 探讨主刀右侧站位在腹腔镜下胃十二指肠溃疡穿孔修补术中的优势.方法 收集2017年1月～2020年12月永州市中心医院冷水滩院区胃肠外科行腹腔镜穿孔修补术治疗的87例胃十二指肠溃疡急性穿孔患者的临床资料.依据主刀站位将其分为右侧站位组(45例)和左侧站位组(42例).比较两组患者的基线资料、术中情况、术后临床指标以及术后2个月随访时的胃镜复查结果.结果 两组患者的基线资料差异无统计学意义(P ＞ 0.05).各组的手术时间及术后并发症的发生率存在差异,有统计学意义(P ＜ 0.05).不同站位对术后并发症的发生有统计学差异(P ＜ 0.05).术中出血量、术后首次排便时间、术后下床活动时间、术后第1天视觉模拟评分法(VAS)评分等,差异无统计学意义(P ＞ 0.05).术后2个月时复查胃镜,两组患者的溃疡均已愈合.结论 主刀右侧站位在腹腔镜穿孔修补术治疗胃十二指肠溃疡穿孔中能方便缝合和术中进行腹腔冲洗及术后引流,缩短手术时间及减少术后并发症的发生率.“,”Objective To explore the advantages of the right position of the main knife in laparoscopic repair of gastroduodenal ulcer perforation. Methods From January 2017 to December 2020, the clinical data of 87 patients with acute perforation of gastroduodenal ulcer who underwent laparoscopic perforation repair in Lengshuitan District of Yongzhou central hospital were collected. According to the position of the main knife, they were divided into right position group (45 cases) and left position group (42 cases). The baseline data, intraoperative conditions, postoperative clinical indicators and gastroscopy results at 2 months follow-up were compared between the two groups. Results There was no significant difference in baseline data between the two groups (P＞0.05). There were significant differences in operation time and incidence of postoperative complications among the groups (P＜0.05). There was no significant difference in intraoperative blood loss, postoperative first defecation time, ambulation time, VAS score on the first day after operation (P＞0.05). There was a statistical difference in the occurrence of postoperative complications (P＜0.05). Two months after the operation, gastroscopy showed that the ulcers of both groups had healed. Conclusion The right position of the main knife in laparoscopic repair of perforation of gastroduodenal ulcer can facilitate suture, intra-abdominal irrigation and postoperative drainage, shorten the operation time and reduce the incidence of postoperative complications.