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作者报告一例严重的SLE患者由于狼疮性血管炎,而引起的急性非结石性胆囊炎.SLE最常见的急性腹部并发症为伴有或不伴肠穿孔的肠系膜缺血和急性胰腺炎,惟并发胆囊炎则从未报告过.患者22岁,女性.有皮肤弥漫性血管炎,血清学检查证实为SLE.肾活检按WHO分类属第4型狼疮性肾炎,旋即开始以类固醇激素和环磷酰胺治疗,6月后重复肾活检有明显好转,即停用环磷酰胺,激素减量,以后一直随访2年,隔日服强的松10mg.以后患者因严重的周围神经病变和多发性单神经炎而住院,当时查抗核因子为1∶2500,2周后即降至1∶500.血清总补体106u/ml(正常115～150).
The authors report a case of acute acalculous cholecystitis in a severely SLE patient due to lupus vasculitis.The most common acute abdominal complications of SLE are mesenteric ischemia and acute pancreatitis with or without intestinal perforation, Cholecystitis has never been reported. The patient was 22 years old and had diffuse vasculitis with serological examination confirmed as SLE. According to WHO classification of renal biopsy is type 4 lupus nephritis, and immediately began to steroids and cyclophosphamide Treatment, repeated renal biopsy in June after a marked improvement, the withdrawal of cyclophosphamide, hormone reduction, after 2 years of follow-up, prednisone 10mg the next day after the patient due to severe peripheral neuropathy and multiple mononeuritis The hospital, then check anti-nuclear factor 1: 2500, 2 weeks after that dropped to 1: 500 serum total complement 106u / ml (normal 115 ~ 150).