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目的探讨糖毒宁方对2型糖尿病患者胰岛素抵抗的影响。方法将入选的80例2型糖尿病患者随机分为治疗组和对照组各40例,治疗组采用糖毒宁方治疗,对照组服用吡格列酮片治疗,治疗前、后观察血糖、血脂、胰岛素、胰岛素抵抗指数、CRP水平变化情况。结果治疗组的总有效率以及改善糖脂紊乱、提高C肽水平、降低胰岛素抵抗指数、CRP等方面均优于对照组,差异具有显著性(P<0.05)。结论糖毒宁方能明显改善2型糖尿病胰岛素抵抗状态。
Objective To investigate the effect of Tangji Decoction on insulin resistance in type 2 diabetic patients. Methods Eighty patients with type 2 diabetes mellitus were randomly divided into treatment group (40 cases) and control group (40 cases). The treatment group was treated with Tangji Decoction and the control group was treated with pioglitazone tablets. Blood glucose, blood lipid, insulin, insulin Resistance index, CRP level changes. Results The total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). It also improved the level of C-peptide, insulin resistance index and CRP. Conclusion Tangjiu Decoction can significantly improve the status of type 2 diabetes insulin resistance.