薄层色谱法鉴别皮炎Ⅰ号中醋酸地塞米松和醋酸曲安奈德

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皮炎Ⅰ号是我院的复方自制制剂,对于夏季性皮炎有良好疗效。处方含醋酸地塞米松、醋酸曲安奈德、薄荷醇、醋酸铝、亮兰等。醋酸地塞米松与醋酸曲安奈德的配伍,不仅由于降低各自用药剂量而减少不良反应,而且也起到治疗协同作用。由于两者结构相近(图1),常规的鉴别试验如碱性酒石酸铜沉淀显色法缺乏专属性,不能判定2种组分均存在,而且也受到着色剂的颜色干扰。为克服 Dermatitis Ⅰ is our hospital compound self-made preparations for the summer of dermatitis have a good effect. Prescriptions include dexamethasone acetate, triamcinolone acetonide, menthol, aluminum acetate, Brilliant Blue and more. The combination of dexamethasone acetate and triamcinolone acetonide not only reduces adverse reactions as it reduces the dosage of each drug, but also acts as a therapeutic synergistic effect. Due to the similar structure (Fig. 1), conventional identification tests, such as the alkaline copper tartrate precipitation method, lack specificity and can not determine that both components are present and are also subject to coloration of the colorant. To overcome
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