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目的:探讨无创正压通气(NIPPV)治疗急性左心衰竭(ALHF)患者的临床疗效。方法:将2013年1月-2014年12月收治的ALHF患者80例分为对照组和治疗组各40例,对照组给予常规药物治疗,治疗组则在对照组的基础上应用NIPPV治疗,比较两组患者急诊入院时即刻、入院后24 h和72 h血浆N-末端原脑利钠肽(NT-pro BNP)水平及疗效。结果 :与对照组相比,治疗组的临床缓解时间、有效率、NT-pro BNP变化均有明显差异(P<0.05);且在治疗72 h后,治疗组NT-pro BNP水平下降更明显(P<0.01)。结论:NIPPV治疗ALHF的疗效确切,值得临床推广应用。
Objective: To investigate the clinical efficacy of noninvasive positive pressure ventilation (NIPPV) in the treatment of patients with acute left heart failure (ALHF). Methods: Eighty ALHF patients admitted from January 2013 to December 2014 were divided into control group and treatment group (n = 40). The control group was given conventional drug treatment. The treatment group was treated with NIPPV on the basis of the control group. The levels of plasma N-terminal pro-brain natriuretic peptide (NT-pro BNP) and the efficacy of the two groups immediately after admission at 24 h and 72 h after admission. Results: Compared with the control group, the clinical remission time, the effective rate and the changes of NT-pro BNP in the treatment group were significantly different (P <0.05); and after 72 hours of treatment, the NT-pro BNP level in the treatment group decreased more obviously (P <0.01). Conclusion: NIPPV treatment of ALHF curative effect is worthy of clinical application.