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多发性硬化是一种中枢神经系统炎性脱髓鞘疾病,组织特征是多灶性血管周围炎性细胞浸润。血脑屏障是存在于脑组织和血液之间的一个复杂的系统,能控制血脑两侧的物质转运,从而保证中枢神经组织内环境的相对稳定。血脑屏障的损伤在多发性硬化中起重要作用。多种因素参与了血脑屏障结构功能的改变,血脑屏障结构功能的变化则与各
Multiple sclerosis is a central nervous system inflammatory demyelinating disease characterized by multifocal perivascular inflammatory cell infiltration. The blood-brain barrier is a complex system that exists between the brain tissue and blood. It can control the substance transport on both sides of the blood-brain so as to ensure the relative stability of the environment in the central nervous system. Damage to the blood-brain barrier plays an important role in multiple sclerosis. A variety of factors involved in the structure and function of the blood-brain barrier changes, changes in the structure and function of the blood-brain barrier and