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胃复安引起锥体外系症状临床杂志报告较少,现将二例报告如下: 例一,男,15岁学生,以呕吐腹泻六小时于1985年3月22日入院。无发烧,神经系统检查:生理反射正常,病理反射未引出。实验室检查:大便常规,黄色稀水样便。脓球(+)白细胞(++)。诊断急性胃肠炎收住院治疗。当日给胃复安片口服一日三次每次5mg,复方新诺明片0.5一日两次。于住院第二天下午患者出现全身肌肉震颤呈阵发性加剧,给安定针10mg肌注后缓解,未停用胃复安。住院第三天发现患者颈强直伴有口角部肌肉痉挛性抽搐,神志清楚,神经系统检查未发现病理征。停用胃复安,给鲁米那针0.1肌注第二天患者锥体外系症状消失。
Metoclopramide caused extrapyramidal symptoms less clinical magazines, now two cases are reported as follows: Example 1, male, 15-year-old student to vomit diarrhea six hours on March 22, 1985 admitted. No fever, neurological examination: normal physiological reflex, pathological reflex did not lead. Laboratory tests: stool routine, yellow watery stools. Pyo (+) white blood cells (++). Diagnosis of acute gastroenteritis admitted to hospital for treatment. The same day to stomach Fuan tablet oral three times a day for each 5mg, 0.5 mg triamcinolone compound twice a day. On the afternoon of the second day of hospitalization, patients experienced systemic paroxysmal muscle tremors exacerbated. Anesthesia was given to 10 mg intramuscularly and relieved. Metoclopramide was not discontinued. On the third day of hospitalization, the patient was found to have ankylotic spasms of the neck with ankylosis of the neck, a conscientious mind, and a pathological sign of neurological examination was not found. Discontinuation of metoclopramide, 0.1 intramuscular injection of luminal needle extrapyramidal symptoms disappeared on the second day.