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目的了解中国糖尿病合并动脉粥样硬化性心血管病患者血压控制及降压药物使用情况,分析影响血压控制的因素。方法对参加“第二项心脏保护研究”临床试验筛选门诊的糖尿病合并动脉粥样硬化性心血管病患者进行调查,记录病史和用药情况,测量血压、BMI和腰围。结果 2007年6月至2009年10月期间,在14个城市共调查6522例患者,平均年龄64岁。70%有高血压病史,其中12%未服任何降压药物,仅18%血压达标。缺血性脑卒中病史(OR 0.70,95%CI 0.58~0.84)和向心性肥胖(OR 0.64,95%CI 0.46~0.89)与血压达标呈负相关。无高血压病史的患者中,64%血压高于130/80 mm Hg。结论我国糖尿病合并心血管病患者血压控制情况距指南要求仍存在很大差距,应注意加强对此类患者的血压控制。
Objective To understand the blood pressure control and the use of antihypertensive drugs in patients with diabetes mellitus and atherosclerotic cardiovascular disease in China and analyze the factors influencing blood pressure control. Methods The patients with diabetes mellitus and atherosclerotic cardiovascular disease participating in “Second Cardiac Protection Research” clinical screening screening clinic were investigated, history and medication were recorded, and blood pressure, BMI and waist circumference were measured. Results From June 2007 to October 2009, a total of 6,522 patients were surveyed in 14 cities, with an average age of 64 years. 70% have a history of hypertension, of which 12% did not take any antihypertensive drugs, only 18% of blood pressure compliance. The history of ischemic stroke (OR 0.70, 95% CI 0.58-0.84) and central obesity (OR 0.64, 95% CI 0.46-0.89) were negatively correlated with blood pressure compliance. Among those without a history of hypertension, 64% had blood pressure above 130/80 mm Hg. Conclusion The blood pressure control in patients with diabetes mellitus and cardiovascular disease in China still has a long way to go from the guideline. Therefore, we should pay attention to the control of blood pressure in these patients.