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线粒体病最早于1959年由Ernster等首先报导,称线粒体肌病综合征,认为是线粒体(mt)基因突变所致。1线粒体与线粒体功能1857年瑞士解剖学家及生理学家阿尔伯特·冯·科立克首先在肌肉细胞中发现的一种颗粒状结构;1890年德国病理学家及组织学家理查德·阿尔特曼将其命名为“原生粒(bioblast)”。1897年,德国科学家
Mitochondrial disease was first reported by Ernster et al in 1959 as Mitochondrial myopathies, which are thought to be caused by mutations in the mitochondrial (mt) gene. 1 Mitochondria and mitochondrial function 1857 Swiss anatomist and physiologist Albert von Koike first found in muscle cells in a granular structure; 1890 German pathologist and histologist Richard Altman names it “bioblast.” In 1897, a German scientist