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目的:观察中心静脉导管置入胸腔联合糖皮质激素治疗结核性胸膜炎的临床效果。方法:将2011.01~2012.08我院收治的结核性胸膜炎患者随机分成观察组40例(中心静脉导管置入胸腔和胸腔内注射糖皮质激素)及对照组38例(中心静脉导管置入胸腔和口服糖皮质激素),比较两组的治疗效果。结果:观察组胸腔积液吸收时间及住院天数均较对照组显著缩短(P<0.05),而两组胸膜反应、胸水包裹及气胸的发生率无显著性差异(P>0.05)。结论:结核性胸膜炎患者特别是合并全身糖皮质激素使用受限患者可选择中心静脉导管置管引流胸腔积液和胸腔内注射糖皮质激素的治疗方法。
Objective: To observe the clinical effect of central venous catheter into thoracic cavity combined with glucocorticoid in the treatment of tuberculous pleurisy. Methods: The patients with tuberculous pleurisy admitted in our hospital from January 2011 to 2012.08 were randomly divided into observation group of 40 cases (central venous catheter into the thoracic and intrathoracic injection of glucocorticoid) and control group of 38 cases (central venous catheter into the thorax and oral glucose Corticosteroids), the treatment effect of two groups were compared. Results: The absorption time of pleural effusion and days of hospitalization in observation group were significantly shorter than those in control group (P <0.05). There was no significant difference in pleural reaction, pleural effusion and pneumothorax between the two groups (P> 0.05). Conclusion: The treatment of patients with tuberculous pleurisy, especially patients with limited use of systemic glucocorticoid, may choose central venous catheter for drainage of pleural effusion and intrathoracic injection of glucocorticoid.