世界范围轮状病毒感染是婴幼儿严重胃肠炎最常见的病因。轮状病毒大约每年在5岁儿童中引起50万例死亡,其中80%发生在发展中国家。在美国,虽然实施免疫前轮状病毒胃肠炎引起的儿童死亡相对较少(每年大约2060例5岁儿童死亡)。在2006年开始轮状病毒疫苗接种规划前,几乎每个儿童 Rotavirus infections worldwide are the most common cause of severe gastroenteritis in infants and young children. Rotavirus causes about 500,000 deaths each year in children of 5 years of age, 80% of them in developing countries. In the United States, although there are relatively few child deaths caused by pre-immune rotavirus gastroenteritis (about 2,060 5-year-old children die each year). Before the start of rotavirus vaccination planning in 2006, almost every child