毛泽东提出要进行马克思列宁主义的普遍真理同中国实际第二次结合的重要思想 ,开启了毛泽东对我国社会主义建设道路和如何有效防止党和国家改变颜色这两大战略性问题的探索。这是关系到社会主义中国命运和前途的两大历史性课题。毛泽东在这两大探索中所积累的经验及其在曲折发展中所提供的教训 ,都有着同样重要的意义。今天 ,我们正面临由于苏东剧变引发的国际形势的巨大变化和国内正进行的历史性变革的关键时刻 ,进一步研究和认识毛泽东这两大探索的重大战略意义 ,在新的历史条件下发展其合理的因素 ,仍然是一个十分重要的历史课题。 Mao Zedong proposed to carry out the important thinking of combining the universal truth of Marxism-Leninism with the reality of China for the second time and started the exploration of Mao Zedong’s approach to the socialist construction in our country and how to effectively prevent the two countries from changing their color. This is the two historic issues that concern the destiny and future of socialist China. Mao Tse-tung’s accumulated experience in these two explorations and his lessons learned in the course of the twists and turns have all the same significance. Today, we are facing a crucial moment of great changes in the international situation triggered by the drastic changes in the Soviet Union and East Europe and a historic change that is taking place in our country. It is of great strategic significance to further study and understand these two major explorations of Mao Tse-tung and to develop under the new historical conditions Reasonable factors are still a very important historical issue.