论文部分内容阅读
Residual bacteria and microleakage in a complicated root canal can often result in reinfection of the periapical tissues.To promote the antibacterial and sealing effects of a root canal filling,core-shell structured CaO/ZnO nanospheres were synthesized using a precipitation method based on a traditional root canal sealer,zinc oxide-eugenol(ZOE).The obtained CaO/ZnO particles had a size of 80-90 nm and a core-shell structure.The film thickness,flow rate,pH,and calcium ion release of the core-shell structured CaO/ZnO nanospheres-eugenol paste were tested.The pH and calcium ion release results showed a slight increase in the prepared nanospheres,with a flow rate of 24.22 mm and a formed film thickness of 30 μm,which are basically consistent with ISO 6876:2001 standards(regarding dental root canal sealing materials).Cytotoxicity tests showed that the cytocompatibility of the CaO/ZnO nanospheres-eugenol paste was much higher than that of the ZOE or iRoot SP groups(P＜0.05).A comparison of the sealing ability and antibacterial activity showed that the core-shell structured CaO/ZnO nanospheres-eugenol paste had significantly better effects than the ZOE and iRoot SP sealers(P＜0.05).The core-shell structured CaO/ZnO nanosphere paste displayed excellent sealing and antibacterial properties,and it has promising application potential in endodontics.