论文部分内容阅读
目的分析高压氧治疗对于老年脑出血患者脑水肿、血浆脑钠肽(BNP)以及脑脊液乳酸(CSF-LA)浓度的影响。方法 80例老年脑出血患者,根据治疗方式分成治疗组与参照组,各40例。参照组使用常规方式治疗,治疗组在参照且基础上实施高压氧治疗。对比两组的治疗效果。结果在入院治疗后第14、21天,两组患者脑水肿体积均有明显减小的趋势,且治疗组比参照组显著,组间对比[(14.29±8.15)ml VS(45.32±11.26)ml、(8.19±6.23)ml VS(29.19±11.23)ml]差异具有统计学意义(P<0.05)。在入院治疗后第14、21、30天,两组患者的CSF-LA都有所降低,并且治疗组降低幅度较参照组明显,组间对比[(3.34±1.02)mmol/L VS(4.86±1.92)mmol/L、(2.15±1.04)mmol/L VS(3.97±1.09)mmol/L、(1.87±0.78)mmol/L VS(2.57±1.21)mmol/L]差异具有统计学意义(P<0.05)。在入院治疗后第14、21、30天,两组患者的血浆BNP浓度都有所降低,并且治疗组降低幅度较参照组明显,组间对比[(115.0±14.2)μg/ml VS(135.0±21.6)μg/ml、(102.0±11.3)μg/ml VS(123.0±18.5)μg/ml、(89.0±10.4)μg/ml VS(108.0±19.0)μg/ml]差异具有统计学意义(P<0.05)。结论在脑出血患者治疗中应用高压氧治疗,可以缩小患者脑水肿体积,降低血浆BNP浓度与CSF-LA,具有应用价值。
Objective To analyze the effect of hyperbaric oxygen therapy on cerebral edema, plasma brain natriuretic peptide (BNP) and cerebrospinal fluid (CSF-LA) in patients with cerebral hemorrhage. Methods Eighty elderly patients with cerebral hemorrhage were divided into the treatment group and the reference group according to the treatment method, 40 cases in each group. The reference group was treated in the usual manner, and the treatment group was treated with hyperbaric oxygen on the basis of the reference. Compare the treatment effect of two groups. Results On the 14th and 21st day after admission, the volume of brain edema in both groups decreased significantly, and the treatment group was significantly more than the reference group [(14.29 ± 8.15) ml vs (45.32 ± 11.26) ml , (8.19 ± 6.23) ml VS (29.19 ± 11.23) ml], respectively (P <0.05). The CSF-LA in both groups decreased on the 14th, 21st and 30th days after admission, and the reduction in the treatment group was more significant than that in the reference group [(3.34 ± 1.02) mmol / L vs 4.86 ± 1.92 mmol / L vs 1.92 mmol / L vs 3.97 ± 1.09 mmol / L vs 1.87 ± 0.78 mmol / L VS 2.57 ± 1.21 mmol / L, P < 0.05). At 14, 21 and 30 days after admission, plasma BNP levels decreased in both groups, and the reduction in the treatment group was more significant than that in the reference group [(115.0 ± 14.2) μg / ml VS (135.0 ± 21.6), (102.0 ± 11.3) μg / ml VS (123.0 ± 18.5) μg / ml and (89.0 ± 10.4) μg / ml VS (108.0 ± 19.0) μg / ml, respectively) 0.05). Conclusions Hyperbaric oxygen therapy can reduce the volume of brain edema and decrease the concentration of plasma BNP and CSF-LA in patients with intracerebral hemorrhage.