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女性,19岁,未婚.1982年2月8日入院.一年前确诊为甲状腺机能亢进,服他巴唑一年,症状明显改善.81年7月以黄药子泡酒,每月泡三斤,一个月服完.二十天前,出现黄疸而停药.否认病毒性肝炎,疟疾,慢性血吸虫病史.体检:皮肤巩膜明显黄染,浅表淋巴结未扪及,无蜘蛛痣,出血点,皮疹及肝掌.甲状腺弥漫性肿大Ⅱ~0,质软,有血管杂音.心尖搏动较散,心率96次,规则,第一心音增强,心尖区吹风样收缩期杂音Ⅲ级,不传导,肺(一).肝上界第五肋间,下界右肋缘下1～2cm,剑突下3cm,质软,轻触痛,脾(一).肝功能总胆红质13.2mg,GPT〉300单位,AKP24.7金氏单位,尿胆红质(十).拟诊:急性药物性肝炎.入院后给予保肝和强的松口服等治疗,一周时黄疸明显减轻,但出现心慌,心率130次.血清甲状腺素含量16.8μg%(正常值4.7～13.0μg%),BMR+4.3%,以甲亢平,心得安,利血平口服.半月后肝功能及
Female, 19 years old, unmarried .82 years old admitted to hospital on February 8, 1982. One year ago was diagnosed with hyperthyroidism, taking methimazole for one year, the symptoms were significantly improved .In July 81 to xanthan sublinguate, three pounds per month, Twenty days before the onset of jaundice and withdrawal. Denied the history of viral hepatitis, malaria and chronic schistosomiasis. Physical examination: Sclera of the skin was clearly yellowed, superficial lymph nodes were not palpable, no spider nevus, bleeding spots, rash And liver palpable thyroid diffuse enlargement Ⅱ ~ 0, soft, vascular murmur.Apex beat more scattered, heart rate 96 times, the rules, the first heart sound enhancement, apical hair-like systolic murmur Ⅲ grade, does not conduct, Lung (a) .The upper intercostal fifth intercostal space, the lower right border of the right rib margin 1 ~ 2cm, xiphoid 3cm, soft, light touch, spleen (a) .The liver function of total bilirubin 13.2mg, GPT> 300 units, AKP24.7 gold units, urine bilirubin (10) .Diagnosed: acute drug-induced hepatitis.After admission to give liver and prednisone oral treatment, jaundice a week was significantly reduced, but there palpitation, heart rate 130 times.Serum thyroxine content of 16.8μg% (normal 4.7 ~ 13.0μg%), BMR + 4.3%, with hyperthyroidism, propranolol, reserpine oral.After half a month liver function and