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A highly efficient green protocol for the preparation of bis-indolylmethanes,bis-2-methylindolylmethanes,bis-1-methylindolylmethanes and 3,3’-diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-free conditions is reported.The significant features of this procedure are high yields of the products,mild reaction,solvent-free condition and non-toxicity of the catalyst.
A highly efficient green protocol for the preparation of bis-indolylmethanes, bis-2-methylindolylmethanes, bis-1-methylindolylmethanes and 3,3’-diindolyloxindole derivatives from the reaction of indoles with various aldehydes and ketones in the presence of cellulose sulfuric acid under solvent-free conditions is reported. significant characteristics of this procedure are high yields of the products, mild reactions, solvent-free conditions and non-toxicity of the catalysts.