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[目的]探讨白血病常用化疗药物治疗后产生的毒副作用及其应对措施。[方法]回顾性分析我院2005年1月~2010年1月期间收治的103例白血病化疗患者的临床资料。[结果]103例白血病患者经化疗后产生的毒副反应有静脉炎、恶心、呕吐、脱发、口腔溃疡、骨髓抑制等,其中18例死亡,23例完成1疗程化疗后未随访,27例完成2疗程化疗,35例经第一次诱导缓解后坚持巩固化疗3疗程以上。[结论]白血病患者化疗用药期间应严格掌握患者的适应症,密切观察不适反应,进行对症治疗和必要的支持治疗,可有效减轻化疗药物对患者的毒副作用和并发症的发生,对提高患者的生存质量具有重要的意义。
[Objective] To explore the toxic and side effects of the commonly used chemotherapy drugs for leukemia and its countermeasures. [Methods] The clinical data of 103 patients with leukemia treated in our hospital from January 2005 to January 2010 were retrospectively analyzed. [Results] 103 patients with leukemia after chemotherapy side effects of phlebitis, nausea, vomiting, hair loss, oral ulcer, bone marrow suppression, of which 18 died, 23 patients completed a course of chemotherapy after the visit was not completed, 27 patients completed 2 courses of chemotherapy, 35 cases after the first induction of remission to adhere to the consolidation of chemotherapy for more than 3 courses. [Conclusion] The patients with leukemia should be strictly controlled during chemotherapy, closely observe the discomfort response, symptomatic treatment and necessary supportive care, which can effectively reduce the side effects and complications of chemotherapy drugs on patients, and improve the patients’ Quality of life is of great significance.