论文部分内容阅读
替硝唑为抗厌氧菌药物,临床应用广泛。近年来国内有文献报道,本品可致双硫仑样反应,现综述如下。任博学报道,例1,患者男,20岁,因牙冠周炎给予替硝唑0.8 g静滴,疗程5 d,愈后第2 d进餐时饮啤酒约640 mL,即感上腹部痉挛,灼烧感;同时伴有头痛、恶心、出冷汗、心悸、呼吸困难;心电图示窦性心动过速,即予对症治疗,1 h后上述症状缓解。例2,患者男,68岁,因牙周脓肿给予本品0.4 g静滴,疗程7 d,预后2 d饮白酒50 mL即出现头痛、胸闷、心前区压榨性疼痛,心电图示窦性心动过速,给予
Tinidazole anti-anaerobic drugs, a wide range of clinical applications. In recent years, there are domestic literature reports, this product can be caused by disulfiram-like reaction, are summarized below. Ren Bo learned that, in Example 1, the male patient, 20 years of age, given tinidazole 0.8 g intravenous infusion of coronary crown periarthritis, the course of treatment 5 d, the second day after drinking beer about 640 mL, that sense of upper abdominal cramps, Burning sensation; accompanied by headache, nausea, cold sweats, heart palpitations, dyspnea; ECG showed sinus tachycardia, that is symptomatic treatment, 1 h after the above symptoms ease. Example 2, male, 68 years old, due to periodontal abscess to give this product 0.4 g intravenous infusion, course of treatment 7 d, 2 d white wine drink 50 mL that headache, chest tightness, precordial press pain, ECG shows sinus heartbeat Too fast, give