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目的:观察老年人氧气雾化吸入盐酸戊乙奎醚在支气管镜诊疗中的临床应用。方法:将114例接受支气管镜诊疗的老年患者,随机分为治疗组和对照组。对照组给予2%利多卡因鼻咽部局部麻醉,治疗组在咽喉部局部麻醉基础上,行支气管镜诊疗前30min加用氧气雾化吸入盐酸戊乙奎醚。分别监测支气管镜检查前、支气管镜进入咽喉部瞬时、检查中、检查结束后即刻、检查结束后10min患者的血压、心率、血氧饱和度、气道分泌物等,评定镇静程度和焦虑程度,观察患者不适反应。结果:治疗组患者监测期间血压、心率、血氧饱和度等水平无明显改变,对照组监测过程中则有较明显改变(P<0.05);治疗组检查过程中的咳嗽程度较对照组小,差异有统计学意义(P<0.05)。结论:雾化吸入盐酸戊乙奎醚作为老年患者的支气管镜检查术前用药时,对老年患者血压和心率等影响甚小,对呼吸道腺体分泌的抑制作用较强,且没有明显的口干等不良反应,可以提高老年患者对支气管镜诊疗的耐受性。
Objective: To observe the clinical application of aerosol inhalation of penehyclidine hydrochloride in bronchoscopy in elderly patients. Methods: Elderly patients who underwent bronchoscopy were randomly divided into treatment group and control group. The control group was given 2% lidocaine nasopharyngeal local anesthesia, the treatment group on the basis of local anesthesia in throat, bronchoscopy 30min before treatment plus oxygen inhalation of penehyclidine hydrochloride. Blood pressure, heart rate, blood oxygen saturation and airway secretions were monitored before bronchoscopy, bronchoscopy into the throat at the moment of instantaneous, during examination, immediately after the examination, and after the examination, to assess the degree of sedation and anxiety, Observe the patient’s discomfort reaction. Results: During the monitoring period, there was no significant change in the blood pressure, heart rate and oxygen saturation in the treatment group, while the changes in the control group were significantly changed (P <0.05). The cough in the treatment group was smaller than that in the control group, The difference was statistically significant (P <0.05). CONCLUSION: Penehyclidine hydrochloride inhalation is superior to bronchoscopy preoperatively in elderly patients, and has little effect on blood pressure and heart rate in the elderly patients. It has a strong inhibitory effect on respiratory glandular secretion and no obvious dry mouth And other adverse reactions, can improve the elderly patients with bronchoscopy diagnosis and treatment tolerance.