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鞣质口服具有收敛作用,能止血、止泻、吸附肠道细菌及其它毒素。外用可与创面蛋白结合形成痂膜,以减少分泌和渗出,保护创面,防止感染加重和扩散。此外鞣质对肝脏有剧毒。但其对心脏的抑制作用则未见有报道。我们在中草药粗提物(水煎醇提物)的降压研究中发现鞣质具有降压作用。以0.1、0.5、1%的鞣质溶液0,5ml/kg分次给家兔静脉注射,给药后血压较给药前分别平均下降23.4±1.94,28.8±3.87,48.4±9.327mmHg,给药前后有显著差异(P<0.001)。给药后心率每分钟较给药前也有不同程度的减慢,其中0.5、1%的鞣质药学通报1984年第19卷第6期
Oral tannin has a convergence effect, to stop bleeding, diarrhea, intestinal bacteria and other toxins adsorption. Topical wounds can be combined with the formation of crust film to reduce the secretion and exudation, protect the wound to prevent infection aggravation and proliferation. In addition tannin is highly toxic to the liver. However, its inhibition of the heart has not been reported. We found that the Chinese herbal medicine extract (decoction extract) of the antihypertensive study found that antihypertensive effect. To 0.1,0.5,1% tannin solution 0,5 ml / kg intravenous injection of rabbits in graded, after administration of blood pressure decreased by an average of 23.4 ± 1.94,28.8 ± 3.87,48.4 ± 9.327mmHg before administration, administration Before and after significant differences (P <0.001). After administration of heart rate per minute than before administration also have varying degrees of slowing down, of which 0.5,1% of tannins Pharmacy Bulletin 1984 Volume 19 No. 6