论文部分内容阅读
目的:探讨临床药师参与肿瘤患者中心静脉置管(PICC)感染合并血栓的药物治疗方案的制定以及提供药学服务的方法。方法:对1例出现PICC感染合并血栓的肿瘤患者,临床药师结合相关指南对抗感染药物及抗血栓药物治疗方案的选择提出了具体意见,建议选用万古霉素治疗导管相关性感染,选用低分子肝素钠预防性抗凝治疗,治疗同时加强凝血功能的药学监护。结果:临床药师的建议被临床医生部分采纳,经治疗后患者的体温恢复正常,深静脉血栓得到良好控制,顺利出院。结论:临床药师通过参与临床实践,可协助医师优化治疗方案,并总结出肿瘤患者PICC感染及深静脉血栓的药学监护模式,为今后的药学监护提供方向。
OBJECTIVE: To investigate the clinical pharmacist’s participation in developing a drug regimen for the treatment of thrombosis complicated with central venous catheter (PICC) in cancer patients and to provide a pharmacy service. Methods: One case of PICC-infected patients with tumor thrombosis, clinical pharmacists combined with relevant guidelines on the choice of anti-infectives and anti-thrombotic drug treatment options, put forward specific recommendations for the use of vancomycin treatment of catheter-related infections, the selection of low molecular weight heparin Sodium prophylactic anticoagulant therapy, treatment while strengthening the pharmacological monitoring of coagulation. Results: The clinical pharmacist’s suggestion was partly adopted by clinicians. After treatment, the patient’s body temperature returned to normal, and deep venous thrombosis was well controlled and discharged smoothly. Conclusion: By participating in clinical practice, clinical pharmacists can help physicians optimize treatment options and summarize the pharmaco-intensive modes of PICC infection and deep venous thrombosis in cancer patients and provide direction for future drug monitoring.