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抗生索或其他化疗药的耐药性和副作用是其治疗淋病受到限制的主要因素,作者报告新的氨基糖甙类药乙基西梭霉素无这些副作用,其疗效已被1200名无并发症淋病患者所证实,尚未观察到耐药菌株.作者在4年间(1982～1985)研究了1200名无并发症的淋病患者(女690,男510)不包括咽部淋球菌感染.女病人从宫颈、尿道和直肠取材,男病人取尿道分泌物及从直肠取材,由涂片直接镜检及培养确诊.予单剂量乙基西梭霉素300mg肌注.7天后再次涂片镜检和培养,结果全部阴转.无严重副作用、变态反应及肾脏和耳中毒的征兆.乙基西梭霉素是从庆大霉素CIa衍生来的半合
Drug resistance and side effects of antibiotic cords or other chemotherapeutic drugs are major factors that limit their treatment for gonorrhea. The authors report that the new aminoglycoside drug, cystathin, does not have these side effects and its efficacy has been surpassed by 1,200 uncomplicated Gonorrhea patients have confirmed that no resistant strains have been observed.The authors studied 1,200 gonorrhea patients without complications (690 males, 510 males) for 4 years (1982-1985) excluding gonorrhea in the pharynx , Urethral and rectal drawing, male patients take urethral secretions and drawn from the rectum, by smear direct microscopy and culture confirmed to single dose of 300 mg intramuscular injection of Sisamycin.After 7 days again smear microscopy and culture, Results all negative. No serious side effects, allergies and signs of kidney and ear poisoning. Ethyl Sisamycin is derived from gentamicin CIa semi