目的:探讨中药复方银苓Ⅰ号对铅中毒小鼠非特异免疫功能的影响。方法:小鼠自由饮用醋酸铅溶液造模,分别予银苓Ⅰ号或依地酸钠钙治疗3周;观察外周血弊细胞计数、碳粒廓清指数K及校正指数α、免疫脏器指数等非特异性免疫功能指标的变化。结果:银苓Ⅰ号对外周血白细胞计数、碳粒廓清指数K及校正指数α、免疫脏器指数有明显改善作用,而且碳粒廓清能力优于依地酸钠钙。结论:银苓号可在一定程度上对抗铅中毒所致的非特异免疫损害,效果优于依地酸钠钙。 OBJECTIVE: To investigate the effect of Chinese herbal compound Yinjing I on non-specific immune function in lead poisoning mice. METHODS: Mice were free to drink lead acetate solution, and were treated with Yinjing I or sodium edetic acid for 3 weeks. The peripheral blood cell count, carbon clearance index K, calibration index α, and immune organ index were observed. Changes in the index of heterosexual immune function. Results: Yinjing I had a significant improvement in peripheral blood leukocyte count, carbon clearance index K, calibration index α, and immune organ index, and carbon particle clearance capacity was superior to sodium edetic acid calcium. Conclusion: Yinhaohao can resist non-specific immune damage caused by lead poisoning to a certain extent, which is better than sodium edetate calcium.