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为探讨乙肝疫苗接种以来儿童肝硬化的发病情况，对２９例小儿肝硬化临床资料进行回顾研究。患病年龄最小３个月，最大１５岁，病程３个月至６年不等。其中，乙肝病毒标志物阳性者９例（３１％），肝豆状核变性８例（２７．１％），提示乙型肝炎肝硬化的发病率仍占首位；小儿肝硬化早期不易发现，定期全面认真体检可减少隐匿性肝硬化的发生。另外，改善营养状况、控制感染，也是减少儿童肝硬化发生的重要环节。
To investigate the incidence of cirrhosis in children since hepatitis B vaccination, the clinical data of 29 pediatric cirrhotic patients were retrospectively studied. The youngest minimum age of 3 months, maximum 15 years old, duration of 3 months to 6 years. Among them, hepatitis B virus markers were positive in 9 cases (31%), hepatolenticular degeneration in 8 cases (27.1%), suggesting that the incidence of hepatitis B cirrhosis is still the first place; early detection of cirrhosis in children is not easy, regular Comprehensive and serious examination can reduce the occult cirrhosis. In addition, to improve nutritional status, infection control, but also reduce the incidence of cirrhosis of children an important part.