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目的探讨尿毒症合并难治性高血压患者使用血液透析滤过(HDF)技术的临床治疗效果。方法选取2011年9月~2014年9月间于我院进行血液透析(HD)的尿毒症伴有难治性高血压患者,共计96例。将上述患者随机分为治疗组和对照组,每组48例,治疗组患者使用HD配合HDF进行治疗,对照组患者仅使用HD进行治疗,对比两组患者的治疗效果、血浆肾素(RA)及血管紧张素(AngⅡ)水平。结果治疗组患者的临床治疗效果明显优于对照组患者(P<0.05)。两组患者治疗后RA及AngⅡ浓度比较差异有统计学意义(P<0.001)。结论对于尿毒症合并难治性高血压患者,我院认为HDF较HD具有更优秀的临床治疗效果,值得临床广泛借鉴和推广。
Objective To investigate the clinical effect of hemodiafiltration (HDF) in uremic patients with refractory hypertension. Methods A total of 96 uremic patients with refractory hypertension undergoing hemodialysis (HD) in our hospital from September 2011 to September 2014 were selected. The above patients were randomly divided into treatment group and control group, 48 cases in each group. The patients in the treatment group were treated with HD with HDF. The patients in the control group were treated with HD alone. The therapeutic effect, plasma renin (RA) And angiotensin (Ang Ⅱ) levels. Results The clinical effect of the treatment group was significantly better than that of the control group (P <0.05). The difference of RA and AngⅡ between the two groups after treatment was statistically significant (P <0.001). Conclusion For patients with uremia complicated with refractory hypertension, our hospital that HDF HD has more excellent clinical effect, it is worth widely clinical reference and promotion.