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分析了43例无排卵性不育患者应用国产人绝经期促性腺激素(HMG)-绒毛膜促性腺激素(hCG)诱发排卵的81个周期中残存卵泡的发生率、促使其发生的因素、对下周期治疗的影响及处理。结果发现:残存卵泡均发生在 hCG 诱发排卵周期,发生率为22.2%。体内有雌激素水平的患者(WHO Ⅱ)发生率(31.3%)比体内无雌激素水平的患者(WHO Ⅰ)发生率(16.3%)高,P<0.05。残存卵泡的发生与应用 hCG 前雌二醇(E_2)值、卵泡数、卵巢大小及卵泡过度刺激综合征(OHSS)有关。残存卵泡直径≤20mm,未经处理而继续 HMG 治疗组卵泡生长速度明显慢于残存卵泡组,P<0.05;但排卵率及妊娠率与无残存卵泡组差异无显著性;残存卵泡直径>20mm 者分为穿刺组和雌孕激素治疗组,两组卵泡生长速度、排卵率和妊娠率与无残存卵泡组差异无显著性。
The morbidity and the factors of residual follicles in 81 cycles of ovulation induced by domestic human menopausal gonadotropin (HMG) - chorionic gonadotropin (hCG) were analyzed in 43 cases of anovulatory infertility patients. The next cycle of treatment and treatment. The results showed that all residual follicles occurred in hCG induced ovulation cycle, the incidence was 22.2%. The incidence of WHO II (31.3%) in vivo was higher than that of the WHO (16.3%) without estrogen in vivo (P <0.05). The occurrence of residual follicles is related to the value of pre-estradiol (E2), number of follicles, ovarian size and ovarian hyperstimulation syndrome (OHSS). The residual follicle diameter ≤20mm, untreated HMG treatment follicle growth rate was significantly slower than the residual follicular group, P <0.05; but the ovulation rate and pregnancy rate and no residual follicular group was no significant difference; residual follicle diameter> 20mm Divided into puncture group and estrogen and progesterone treatment group, the two groups of follicle growth rate, ovulation rate and pregnancy rate and no residual follicular group no significant difference.