论文部分内容阅读
第二次世界大战后,由于有效的抗疟药物氯喹和乙胺嘧啶的问世及长效杀虫剂DDT等的使用,疟疾防治工作取得了卓越成绩。1955年世界卫生会议和1957年世界卫生组织疟疾专家委员会分别提出了消灭全球疟疾的倡议和规划。1967年前执行规划比较顺利,以后趋于停滞不前乃至倒退的状态。目前不少国家和地区把灭疟方案退到了控制疟疾的地位。灭疟规划面临的困难,既有政治经济方面的原因,也有技术方面的原因,尤以恶性疟原虫对最常用的抗疟药氯喹产生抗性是实施灭疟规划的主要障碍。
After World War II, malaria control achieved outstanding results due to the advent of effective anti-malarial drugs such as chloroquine and pyrimethamine and the use of long-acting insecticide DDT. The 1955 World Health Assembly and the 1957 World Health Organization’s Malaria Expert Committee proposed initiatives and plans to eradicate malaria worldwide. The implementation plan before 1967 was relatively smooth, and later tended to stagnate or even regress. At present, many countries and regions have put the plan to eliminate malaria back to the control of malaria. The difficulties in planning for the elimination of malaria, both politically and economically, and also for technical reasons, in particular the resistance of Plasmodium falciparum to chloroquine, the most commonly used antimalarial drug, constitute a major impediment to planning for malaria elimination.