造影剂的临床应用始于20年代,数十年来用于心血管造影、胆系和泌尿系造影的造影剂,一直都是碘剂,其中对用于心血管造影,也即泌尿系造影的碘剂的研究最为广泛。一切研究目的都在于找到一种安全的即没有或很少引起副反应的造影剂,使其可大量和高浓度地用于血管内注射。尽管如此,注射造影剂后发生严重反应,甚至致命者仍有发生。为此,对于近年来造影剂及其副反应的发展作一复习,以期更好地使用造影剂。 The clinical application of contrast media began in the 1920s and has been used for several decades as a contrast agent for cardiovascular angiography, biliary and urological imaging, and has been used as an agent for iodine, of which iodine for angiography, that is, urography The most extensive study of agents. The goal of all research is to find a safe contrast agent that has little or no side effects, allowing it to be used in large quantities and at high concentrations for intravascular injection. In spite of this, a serious reaction occurred after injecting the contrast agent, and even the fatal person still occurred. To this end, for the recent years, contrast agents and the development of side effects to make a review, in order to better use of contrast media.