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目的:探讨枸橼酸氯米芬与戊酸雌二醇联合治疗排卵障碍性不孕症的临床疗效。方法:对我院2015年1月至12月期间收治的170例排卵障碍性不孕症患者的临床资料进行回顾性分析,将所有患者根据随机数字表法分为对照组和研究组,每组85例,对照组患者采用枸橼酸氯米芬治疗,研究组患者采用枸橼酸氯米芬与戊酸雌二醇联合治疗,对比两组患者临床治疗效果及不良反应发生情况。结果:研究组治疗总有效率为92.94%(79/85),对照组治疗总有效率为76.47%(65/85),两组比较差异性显著(P<0.05),两组均未发生严重的不良反应,组间比较无显著性差异(P>0.05)。结论:枸橼酸氯米芬与戊酸雌二醇联合应用能有效不孕症的治疗效果,且不良反应少,具有重要的临床应用价值。
Objective: To investigate the clinical efficacy of clomiphene citrate and estradiol valerate in the treatment of ovulatory dysplasia. Methods: A retrospective analysis was performed on the clinical data of 170 patients with infertility due to ovulatory dysfunction admitted to our hospital from January to December 2015. All patients were divided into control group and study group according to random number table. Each group 85 patients in the control group were treated with clomiphene citrate. The study group was treated with clomiphene citrate and estradiol valerate, and the clinical effects and adverse reactions of the two groups were compared. Results: The total effective rate was 92.94% (79/85) in the study group and 76.47% (65/85) in the control group, with significant difference between the two groups (P <0.05), and no significant difference was found between the two groups There was no significant difference between the two groups (P> 0.05). Conclusion: The combination therapy of clomiphene citrate and estradiol valerate can effectively treat infertility without adverse reactions, and has important clinical value.