对武汉滨湖制药厂生产的三批甲硝唑注射液(家兔热原检查均合格)进行了细菌内毒素的检测试验,同时设立在阳性及阴性对照下,共作了3方面的研究:①按中国药典1990版第2增补版“细菌内毒素检查法”操作,对厦门鲎试剂厂出口的批号为940904、950301两批鲎试剂标定,得到的灵敏度是0.25EV/ml;②按中国药典1990版计算得到该3批样品细菌内毒素理论限值为3.33EV/ml,样品的最 Three batches of metronidazole injection (rabbit pyrogen test were qualified) produced by Binhu Pharmaceutical Factory in Wuhan were tested for bacterial endotoxin. At the same time, three tests were done under the positive and negative control. ① According to the 1990 edition of the Chinese Pharmacopoeia, the second supplement, “Bacterial Endotoxin Test” operation, Xiamen Huang reagent plant export batch number 940904, 950301 two batches of 鲎 reagent calibration, the sensitivity is 0.25EV / ml; ② Chinese Pharmacopoeia Calculated in 1990 version of the three batches of bacterial endotoxin theoretical limit of 3.33EV / ml, the most sample