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对１７８例原发性肺癌患者血清唾液酸（ＳＡ）含量、铜／锌（Ｃｕ／Ｚｎ）比值进行了测定分析，并与８０例正常人作对照。结果表明：原发性肺癌患者血清ＳＡ含量（１２２．２０±３６．３０）、Ｃｕ／Ｚｎ比值显著高于对照组，（Ｐ＜０．０１）。单项检测：两项指标对肺癌的诊断敏感性分别为７６．４％和６１．２％，特异性为９７．５％和７６．３％；联合检测：以两项之一阳性为诊断依据时，特异性可达９８．７％。表明ＳＡ和Ｃｕ／Ｚｎ比值联合检测较单项检测对肺癌的诊断更有临床应用价值。
The serum sialic acid (SA) content and copper/zinc (Cu/Zn) ratio of 178 patients with primary lung cancer were analyzed and compared with 80 normal controls. The results showed that serum SA levels (122.20±36.30) and Cu/Zn ratio were significantly higher in patients with primary lung cancer than in the control group (P<0.01). Single test: The diagnostic sensitivity of the two indexes for lung cancer was 76.4% and 61.2%, and the specificity was 97.5% and 76.3%. Combined detection: When one of the two items was positive for diagnosis The specificity can reach 98.7%. It was shown that the combined detection of SA and Cu/Zn ratios had more clinical value in the diagnosis of lung cancer than single detection.