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盐酸左氧氟沙星注射液为第三代喹诺酮类抗菌药物,是氧氟沙星左旋体的盐酸盐水合物,通过抑制细菌DNA旋转酶的活性,阻碍细菌DNA的复制而达到抗菌作用,适用于敏感细菌所引起的呼吸系统、泌尿系统、生殖系统、皮肤软组织等中、重度感染。近年来,在临床工作中常发现盐酸左氧氟沙星注射液与多种药物存在配伍禁忌,尤其是抗生素和中成药,这引起医务工作者的重视。笔者经搜索近年来报道的文献资料,现对盐酸左氧氟沙星注射液配伍禁忌综述如下。
Levofloxacin hydrochloride injection for the third generation of quinolone antibacterial drugs, isloxacin hydrochloride L-hydrochloride hydrate, by inhibiting the activity of bacterial DNA gyrase, hinder the replication of bacterial DNA to achieve antibacterial effect, suitable for sensitive bacteria Caused by the respiratory system, urinary system, reproductive system, skin and soft tissue, etc., severe infection. In recent years, often found in clinical work levofloxacin hydrochloride injection with a variety of drugs compatibility taboo, especially antibiotics and proprietary Chinese medicines, which attracted the attention of medical workers. The author after searching the literature reported in recent years, are now on the levofloxacin hydrochloride injection incompatibility are summarized below.