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报告6例发病时间在4～10小时内的急性心肌梗塞患者，采用冠状动脉狭窄口堵塞近端注入东菱克栓酶（DF－521）20～30BU（Batroxobinunit简称BU，是Batroxobin的酶活性量的表示单位。37℃以下，标准人～枸椽酸血浆0．3ml中加入Batroxobin溶液0．1ml，19．0±0．2秒发生凝固时其酶活性为2BU）。进行溶栓治疗，60～90分钟后重复冠状动脉造影。结果全部有效，4例闭塞管腔再通（TIMI达Ⅲ级）2例大部分再通（TIMI达Ⅱ级），从而限制了梗塞发展且无出血及其它并发症，效果显著，值得进一步研究推广。
6 cases of acute myocardial infarction with onset time of 4 ~ 10 hours were reported. The proximal part of coronary artery stenosis was implanted with 20 ~ 30BU of Batroxobinunit (DF), which is the enzyme activity of Batroxobin Of the units below 37 ° C, standard human ~ citrate plasma 0.3ml added Batroxobin solution 0.1ml, 19.0 ± 0.2 seconds when the coagulation occurs when the enzyme activity 2BU). Thrombolytic therapy, 60 to 90 minutes after coronary angiography. The results were all valid. The results of 4 cases of recanalization of the lumen (TIMI grade Ⅲ) were mostly recanalization (TIMI grade Ⅱ), which limited the development of infarction and had no complications of hemorrhage and other complications, which deserved to be further studied. .