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患者徐××,男性,60岁,1991年11月干部体检时B超发现右肾占位性病变,后经CT诊断为右肾癌.于当年11月20日行右肾切除术,术后病理报告原发性肾细胞癌.当时经全面检查未发现有其它脏器转移,当患者拒绝化疗而出院,并回单位正常工作.1992年12月初无明显诱因出现阵发性剧咳,痰中带血,于12月12日来我院就诊,胸片报告为双肺转性肺癌,收入院治疗.入院后复查肺部CT示肺散在转移灶,左肺最大为3cm×3cm,右肺最大为2cm×3cm.1992年12月14日首次在X光监视下行皮穿刺肺动脉留置导管药物灌注术,首次灌注表阿霉素30mg、卡铂300mg、丝裂霉素12mg,各分3天灌注,并每天灌注白细胞介素Ⅱ30万∪,同种异体LAK细胞1×10~9/100ml,间隔1个月再行第2次灌注,剂量、药物同前.2次灌注间隔期每日肌注白介素Ⅱ10万∪,每2次灌注为一周期.
Patients Xu × ×, male, 60 years old, November 1991 cadres physical examination B-found right renal space-occupying lesions, after diagnosis of right renal cell carcinoma by CT. On November 20 that year, the right nephrectomy, postoperative Pathological report of primary renal cell carcinoma .At that time, after a comprehensive examination found no other organ metastases, when the patient refused to chemotherapy and discharged, and back to the normal work unit .1992 December no significant incentive paroxysmal dramatic cough, sputum Bloody, came to our hospital on December 12, chest X-ray lung biopsies reported, admission hospital treatment .After admission, lung CT showed pulmonary scattered in the metastasis, the maximum left lung 3cm × 3cm, the largest right lung For the first time in December 14, 1992 under the X-ray skin catheterization of pulmonary artery catheterization drug perfusion, the first perfusion of epirubicin 30mg, carboplatin 300mg, mitomycin 12mg, each 3-day perfusion, And every day perfusion of interleukin Ⅱ 230 000 同, allogeneic LAK cells 1 × 10 ~ 9 / 100ml, interval of 1 month and then the second perfusion, dose, drug with the former .2 perfusion interval intramuscularly interleukin Ⅱ 10 million ∪, every 2 perfusion for a period.