论文部分内容阅读
观察了经腹腔注射低剂量三氯化钐（００５ｍｇ／ｋｇ）对链脲佐菌素引起的非胰岛素依赖型糖尿病（ＮＩＤＤＭ）大鼠胰岛形态和功能的影响。结果表明，三氯化钐治疗组糖耐量改善、血清胰岛素水平升高（Ｐ＜００５）、血清胰高血糖素水平降低（Ｐ＜００１）、平均单个胰岛面积和胰岛β细胞数量明显增多（Ｐ＜００５）、肝细胞内糖原含量增多。提示低剂量三氯化钐对实验性ＮＩＤＤＭ大鼠有一定的治疗作用。
The effect of low dose of samarium trichloride (005 mg / kg) intraperitoneally on the islet morphology and function of streptozotocin-induced non-insulin-dependent diabetes mellitus (NIDDM) rats was observed. The results showed that the treatment with samarium chloride improved glucose tolerance, serum insulin levels increased (P <0 05), serum glucagon levels decreased (P <0 01), the average single islet area and the number of pancreatic β cells Significantly increased (P <0 05), liver glycogen content increased. Tip low dose of samarium chloride on experimental NIDDM rats have a certain therapeutic effect.