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[目的]探讨肝动脉介入热灌注化疗栓塞联合CT引导下射频消融(RFA)治疗肝脏恶性肿瘤的临床应用价值。[方法]48例肝脏恶性肿瘤随机分为联合组(24例)和对照组(24例),联合组采取肝动脉介入热灌注化疗栓塞联合RFA治疗,对照组仅行肝动脉介入热灌注化疗栓塞治疗。治疗后通过影像学及相关肿瘤标志物等进行疗效评价。[结果]联合组和对照组临床治疗有效率分别为70.8%和41.6%;两组患者甲胎蛋白(AFP)下降率和转阴率分别为66.7%、33.3%和30.7%、0。[结论]肝动脉介入热灌注化疗栓塞联合RFA是肝脏恶性肿瘤的一种有效治疗方法。
[Objective] To investigate the clinical value of transcatheter arterial chemoembolization combined with CT-guided radiofrequency ablation (RFA) in the treatment of hepatic malignancies. [Method] Forty-eight cases of malignant liver tumors were randomly divided into combined group (24 cases) and control group (24 cases). In the combined group, hepatic artery interventional thermal-infusion chemoembolization combined with RFA was used. In the control group, only hepatic artery interventional thermal-infusion chemoembolization treatment. After treatment through imaging and related tumor markers for efficacy evaluation. [Results] The effective rates of clinical treatment in combined group and control group were 70.8% and 41.6% respectively. The declining rate and negative conversion rate of AFP in two groups were 66.7%, 33.3% and 30.7%, respectively. [Conclusion] Hepatic artery interventional thermochemoembolization combined with RFA is an effective treatment for hepatic malignancies.