目的 调查体外循环术后患者在ICU停留时间延长的发生率及其危险因素.方法 回顾性分析2015年6月至2017年6月广州市某三级甲等医院接受体外循环术的395例患者.数据从医院电子信息系统中获取.采用Logistic多元回归分析对患者ICU停留时间延长的危险因素进行分析.结果 体外循环患者术后ICU停留时间延长(＞72.0 h)的发生率为34.7％(137/395),ICU停留时间的中位数为50.9 h.Logistic多元回归分析结果显示,患者ICU停留时间延长与多重因素有关,包括体外循环时间、机械通气时间延长、应用无创辅助通气、术后6 h氧合指数、手术类型、术中红细胞输入、术后房性心律失常和术后室性心律失常(P＜0.05).结论 关注体外循环术后患者的危险因素可以帮助早期识别ICU停留时间延长的患者,临床医务人员可早期对其进行干预以降低风险,以防患者康复时间延长.“,”Objectives:Patients after cardiac surgery with cardiopulmonary bypass(CPB)require a stay in the ICU postoperatively.This study aimed to investigate the incidence of prolonged length of stay(LOS)in the ICU after cardiac surgery with CPB and identify associated risk factors.Methods:The current investigation was an observational,retrospective study that included 395 ICU patients who underwent cardiac surgery with CPB at a tertiary hospital in Guangzhou from June 2015 to June 2017.Data were obtained from the hospital database.Binary logistic regression modeling was used to analyze risk factors for prolonged ICU LOS.Results:Of 395 patients,137(34.7％)had a prolonged ICU LOS(＞72.0 h),and the median ICU LOS was 50.9 h.Several variables were found associated with prolonged ICU LOS:duration of CPB,prolonged mechanical ventilation and non-invasive assisted ventilation use,Pa02/Fi02 ratios within 6 h after sur-gery,type of surgery,red blood cell infusion during surgery,postoperative atrial arrhythmia,post-operative ventricular arrhythmia(all P＜0.05).Conclusions:These findings are clinically relevant for identifying patients with an estimated prolonged ICU LOS,enabling clinicians to facilitate earlier intervention to reduce the risk and prevent resulting delayed recovery.