先前曾用嵌合体果蝇来筛查细胞增殖的肿瘤抑制基因或负调控因子。这些果蝇的细胞成分与带有少量变异体细胞的癌症病人个体相似 ,lats(也被称为 wts)是一个大的肿瘤抑制基因 ,推测此基因编码色氨酸 /苏氨酸激酶 ,lats体细胞突变是细胞过度增殖并在嵌合体的许多组织中形成大的肿 Chimeric Drosophila has previously been used to screen tumor suppressor genes or negative regulators of cell proliferation. The cellular components of these Drosophila are similar to those of cancer patients with a small number of variant cells. The lats (also called wts) is a large tumor suppressor gene, presumably encoding the tryptophan/threonine kinase, lats body Cellular mutations are cells that proliferate excessively and form large swollen masses in many tissues of the chimera