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目的应用多模式诱发电位评估缺氧性脑病脑功能损伤程度和预测预后的准确性。方法对44例心肺复苏后、低血压和(或)低血氧导致的昏迷患者进行体感诱发电位、脑干听觉诱发电位监测,并根据Judson、Hall、Cant、Haupt标准进行单模式、多模式以及单模式与多模式之间的比较。结果单模式和多模式各分级标准与预后均有显著相关性,级别越高,预后越差。体感诱发电位预测准确性(Judson标准为84.1%)高于脑干听觉诱发电位(Hall标准为79.5%)。多模式诱发电位预测准确性(Cant标准为88.4%)高于单模式诱发电位。结论多模式诱发电位能更好地反映缺氧性脑病的脑功能损伤程度,Cant标准简便易行,预测准确性高,适于临床推广应用。
Objective To evaluate the degree of brain damage induced by hypoxic encephalopathy and the accuracy of prognosis by using multimodal evoked potentials. Methods The somatosensory evoked potentials and brainstem auditory evoked potentials were monitored in 44 patients with coma after hypoxemia and / or hypoxemia after cardiopulmonary resuscitation (CPR). Single-mode, multi-mode and Comparison between single-mode and multi-mode. Results The results of single-mode and multi-modal classification showed significant correlation with prognosis. The higher the grade, the worse the prognosis. The prediction accuracy of somatosensory evoked potentials (Judson standard was 84.1%) was higher than brainstem auditory evoked potentials (Hall standard was 79.5%). The accuracy of multimodal evoked potentials (Cantonese standard was 88.4%) was higher than that of single mode evoked potentials. Conclusions Multimodal evoked potentials can better reflect the damage of brain function in hypoxic encephalopathy. Cant standard is simple and easy to operate with high predictive accuracy and is suitable for clinical application.