作者报道对有发生黄斑全层裂孔危险的15眼作玻璃体切割术的临床表现。对象与方法:15例患者(男7、女8),年龄53～78岁(平均67岁)。所有患者均有视力下降。裂隙灯检查见中心凹光反射消失,中心凹视网膜隆起并伴有黄色环,某些病例玻璃体与中心凹之间有牵拉。对侧眼中,9例有黄斑全层裂孔,1眼为Ⅰ期黄斑裂孔,1眼为先天性弓形体病瘢痕,4眼正常。11例术前曾作中心凹视网膜电图(ERG)。术后检查包括最佳矫正视力和黄斑部观察,作过ERG的11眼术后有6眼作了中心凹ERG。黄斑部改变按Gass的分类法分成两期。黄斑裂孔Ⅰ期眼 The authors report the clinical presentation of vitrectomy for 15 eyes at risk for macular hole. Subjects and methods: 15 patients (male 7, female 8), aged 53 to 78 years (mean 67 years). All patients have vision loss. Slit lamp examination to see the foveal reflex disappears, foveal retinacal uplift and accompanied by a yellow ring, in some cases between the vitreous and the fovea stretch. In the contralateral eyes, there were 9 cases of macular hole, 1 case of stage Ⅰ macular hole, 1 case of congenital toxoplasmosis scars, 4 cases of normal. Eleven patients had a foveal electroretinogram (ERG) preoperatively. Postoperative examinations included best-corrected visual acuity and macular observation. Of the 11 eyes that had undergone ERG, 6 had foveal ERG. Macular changes are grouped according to Gass’s classification into two phases. Macular hole Ⅰ eye