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作者用吡喹酮治疗了141例神经系统囊虫病病人,男性72例(51%),女性69例(49%),年龄8月-72岁(平均35岁)。78例有颅内高压或头痛,63例有癫痫发作,61例有易变的眼症状,45例平衡失调,21例智力障碍,5例有脊髓综合征。将病人分为两组,第一组76例仅用吡喹酮治疗,第二组65例用吡喹酮的同时还用强的松(30mg/日)。吡喹酮的剂量为50mg/kg/日,15天为一疗程,治疗前后均做完整的CSF检查及囊虫病补体结合试验和血细胞凝集试验,每个病人至少随访5年。第二组有38例以往曾行手术以缓解颅内高压。二组病人经上述药物治疗后,有20例作了手术治疗以改善复发性或持久性颅内高压,其中14例作脑室分流术,1例需手术减压,5
The authors treated 141 patients with neurocysticercosis with praziquantel, 72 (51%) men and 69 women (49%) with a mean age of 35 years. Seventy-eight patients had intracranial hypertension or headache, 63 had seizures, 61 had variable ocular symptoms, 45 had imbalances, 21 had mental retardation, and 5 had spinal syndrome. The patients were divided into two groups, the first group of 76 patients treated with praziquantel only, the second group of 65 patients treated with praziquantel and prednisone (30mg / day). Praziquantel dose of 50mg / kg / day, 15 days for a course of treatment before and after treatment are done a complete CSF check and cysticercosis complement fixation test and hemagglutination test, each patient at least 5 years follow-up. The second group of 38 patients had surgery in the past to relieve intracranial hypertension. Two groups of patients after the above drug treatment, 20 cases were treated to improve the treatment of recurrent or persistent intracranial hypertension, of which 14 cases of ventricular shunt, 1 case required surgical decompression, 5