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目的:提高对硬皮病的认识,减少结缔组织病误诊的发生。方法:回顾分析1例硬皮病合并肺间质疾病误诊的经过。结果:患者因胸闷、活动后气促、皮肤瘙痒来就诊,入院后经肺组织活检、皮肤活检、胸部增强CT等确诊为硬皮病合并肺间质疾病,行小剂量激素及免疫抑制剂治疗后,前述症状有所好转。结论:临床上不明原因的呼吸系统疾病,可能由硬皮病引起。
Objective: To improve the understanding of scleroderma and reduce the occurrence of connective tissue disease misdiagnosis. Methods: One case of misdiagnosis of scleroderma with pulmonary interstitial disease was retrospectively analyzed. Results: Patients with chest tightness, shortness of breath after activity, pruritus and skin treatment, after admission by lung biopsy, skin biopsy, chest enhanced CT were diagnosed as scleroderma with interstitial lung disease, low-dose hormone and immunosuppressive therapy After the above symptoms have improved. Conclusion: Clinically unexplained respiratory disease may be caused by scleroderma.