论文部分内容阅读
［目的］评价术前肠系膜上、下动脉灌注抗癌药物治疗大肠癌的组织学疗效及其临床价值。［方法］术前病理证实的５１ 例大肠癌经选择性肠系膜上、下动脉插管灌注抗癌药物１至２次，５至３０天，平均１２天后手术切除，标本送病理切片行组织学疗 效观察。［结果］肿瘤组织学疗效０级１例，Ⅰ级２１例，Ⅱ级２４例，Ⅲ级５例，总有效率９８０％，１６例淋巴结转移，其组织学疗效０ 级５例，Ⅰ级５例，Ⅱ级５例，Ⅲ级１例，总有效率６８ ８％。［结论］术前动脉灌注抗癌药物治疗大肠癌组织学疗效显著，可降低淋巴 结转移率。
[Objective] To evaluate the histological efficacy and clinical value of preoperative mesenteric and inferior arterial infusion anticancer drugs for colorectal cancer. [Methods] Preoperative pathologically confirmed 51 cases of colorectal cancer were infused with anticancer drugs through selective mesenteric and inferior arterial intubation for 1 to 2 times for 5 to 30 days. After an average of 12 days, surgical resection was performed. The specimens were sent to pathological sections for histological efficacy. Observed. [Results] The histological effect of tumor was grade 1 in grade 1, grade I in 21, grade II in 24, grade III in 5, total effective rate 98%, lymph node metastasis in 16 cases, histological efficacy was 0 in 5 cases, grade I 5 Cases, 5 cases of grade II, 1 case of grade III, total effective rate of 688%. [Conclusion] Preoperative arterial infusion of anti-cancer drugs has significant histological effects on colorectal cancer and can reduce the lymph node metastasis rate.