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目的:探讨苯妥英钠在人工流产术中的疗效。方法:人工流产术前2h随机选择30例孕妇口服苯妥英钠200mg作为观察组,30例孕妇口服安慰剂作为对照组。观察镇痛效果、全身综合反应、宫颈松弛程度、平均出血量等。结果:观察组宫颈松弛度、镇痛效果、全身情况与对照组比较有显著差异(P<0.05),出血量无明显增多。结论:苯妥英钠可有效松弛宫颈,减轻术时疼痛,无副作用,药源丰富,价格低廉,应用方便,不失为一种安全、实用、经济的人工流产术镇痛方式。
Objective: To investigate the efficacy of phenytoin in induced abortion. Methods: 30 cases of pregnant women were randomized to receive phenytoin 200 mg 2 hours before induced abortion. 30 pregnant women were given oral placebo as control group. Observation of analgesic effect, generalized systemic response, cervical relaxation, the average amount of bleeding. Results: In the observation group, cervical relaxation, analgesic effect and systemic conditions were significantly different from those in the control group (P <0.05). No significant increase in bleeding volume was observed. Conclusion: Phenytoin sodium can effectively relax the cervix, relieve the pain during operation, have no side effect, abundant drug sources, low price and convenient application. It is a safe, practical and economical analgesia for abortion.