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伊曲康唑(商品名斯皮仁诺)为新一代广谱口服抗真菌药。本文对366例真菌性阴道炎患者使用伊曲康唑治疗,取得满意疗效,现报道如下。 1 临床资料 1.1 一般资料 本组病例为1996年5月20日—1998年5月20日我院门诊妇科病人。主诉:外阴痒,痛、白带增多。检查见阴道分泌物呈豆渣样或凝乳块,外阴、阴道充血。白带涂片直接镜检念珠菌(+)或口服抗真菌药物史的已婚非妊娠妇女366例。平均年龄32.6岁,平均病程27.5 d。 1.2 药物及给药方法 本组均采用西安杨森公司生产的伊曲康唑冲击量1日疗法:400 mg分两次口服。 1.3 随访 ①时间:用药后7～10 d(近期)及25～30 d(远期),非经期复查2次。②内容:记录症状、体征(妇科检查情况)及阴道分泌物涂片或培养找真菌。
Itraconazole (trade name Sporanox) is a new generation of broad-spectrum oral antifungal. 366 cases of fungal vaginitis patients with itraconazole treatment, and achieved satisfactory results, are reported below. 1 Clinical data 1.1 General Information The group of patients for May 20, 1996 - May 20, 1998 outpatient gynecological patients. Chief complaint: genital itching, pain, increased vaginal discharge. Check the vaginal discharge was found in soy-like residue or curd block, vulva, vaginal congestion. 366 cases of married non-pregnant women with leucorrhea smear direct microscopic examination of Candida (+) or oral antifungal drug history. The average age was 32.6 years, the average duration of 27.5 d. 1.2 drugs and methods of administration This group are used in Xi’an Yang Sen production of itraconazole impact on the 1st treatment: 400 mg twice orally. 1.3 follow-up ① time: 7 to 10 days after treatment (short-term) and 25 to 30 days (long-term), non-recheck 2 times. ② content: record the symptoms, signs (gynecological examination) and vaginal discharge smear or culture to find fungi.