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近年来,通过自组装技术能够可控地将单个纳米颗粒组装成一维、二维或三维空间构象的新型复合材料.相对于单独的纳米颗粒,纳米颗粒组装材料可表现出许多新颖或优异的物理性质,具有巨大的应用前景,因此在纳米材料领域越来越受到关注并快速发展.尤其是贵金属纳米颗粒组装体具有独特的等离子激元光学性质,在生物传感、成像和治疗等方面具有广阔的应用前景.本文回顾了近年来通过分子介导方法对纳米颗粒进行组装及其生物应用的最新研究进展,重点介绍了几种分子介导的纳米颗粒组装技术,以及纳米颗粒组装体的生物医学应用,并展望了其发展前景.
In recent years, individual nanoparticles can be controllably assembled into new composite materials in one-, two-, or three-dimensional spatial conformation by self-assembly techniques Nanoparticle assembly materials can exhibit many novel or superior physical properties relative to individual nanoparticles Nature, has great application prospects, so in the field of nanomaterials more and more attention and rapid development.In particular, the noble metal nanoparticle assembly has a unique plasmon optical properties, in the biosensing, imaging and treatment has a vast .This paper reviewed the latest research progress on the assembly and biological application of nanoparticles by molecular-mediated methods in recent years, and mainly introduced several molecular-mediated nanoparticle assembly technologies and the biomedical Application, and prospects of its development prospects.