作者曾对32名患有哮喘的小儿作色氨酸负荷试验,发现他们犬尿烯酸(Kynurenic acid)及黄尿烯酸(Xanthurenic acid)排泄增多。后作者又以维生素B_6治疗5名严重哮喘患儿,先给50毫克/日,并无明显效果,逐将剂量增至100毫克/天,则症状改善且犬尿烯酸及黄尿烯酸的排泄亦接近正常。其后,又对76名 The authors tested the tryptophan burden of 32 asthmatic children and found that their kynurenic and excretion of xanthurenic acid increased. After the author and vitamin B_6 treatment of five children with severe asthma, first give 50 mg / day, no significant effect, by the dose to 100 mg / day, the symptoms improved and kynurenic acid and uronate Excretion is also close to normal. After that, another 76